Small molecules which mimic ACVR1 KO
Canned Analysis
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General Information
AccessionDCA00022235
TitleSmall molecules which mimic ACVR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ACVR1 KO in the whole uterine tissues cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f60e467bea600fbaf14
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2520
Cell Typewhole uterine tissues
Gene Symbol (human)ACVR1
Gene Symbol (mouse)Acvr1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1134058, GSM1134059, GSM1134060
Perturbed SamplesGSM1134061, GSM1134062, GSM1134063
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE46689
Gene Expression Omnibus
Gene expression profiling of Activin-like kinase 2 knockout in mice
7
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