Small molecules which reverse S1PR2 KO
Canned Analysis
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General Information
AccessionDCA00022240
TitleSmall molecules which reverse S1PR2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by S1PR2 KO in the neocortex, male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f47e467bea600fbaf0a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2524
Cell Typeneocortex, male
Gene Symbol (human)S1PR2
Gene Symbol (mouse)S1pr2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM172927, GSM172928, GSM172929, GSM172930, GSM172931
Perturbed SamplesGSM172937, GSM172938, GSM172939, GSM172940, GSM172941
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7191
Gene Expression Omnibus
Altered gene expression in the neocortices and hippocampi of the adult S1P2-deficient and S1P3-deficient mice
56
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