Small molecules which mimic S1PR3 KO
Canned Analysis
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General Information
AccessionDCA00022243
TitleSmall molecules which mimic S1PR3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by S1PR3 KO in the neocortex, male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f32e467bea600fbaf00
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2526
Cell Typeneocortex, male
Gene Symbol (human)S1PR3
Gene Symbol (mouse)S1pr3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM172927, GSM172928, GSM172929, GSM172930, GSM172931
Perturbed SamplesGSM172947, GSM172948
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7191
Gene Expression Omnibus
Altered gene expression in the neocortices and hippocampi of the adult S1P2-deficient and S1P3-deficient mice
56
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