Small molecules which reverse S1PR3 KO
Canned Analysis
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General Information
AccessionDCA00022246
TitleSmall molecules which reverse S1PR3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by S1PR3 KO in the neocortex, female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22ecfe467bea600fbb5e2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2551
Cell Typeneocortex, female
Gene Symbol (human)S1PR3
Gene Symbol (mouse)S1pr3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM172932, GSM172933, GSM172934, GSM172935, GSM172936
Perturbed SamplesGSM172949, GSM172950, GSM172951
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7191
Gene Expression Omnibus
Altered gene expression in the neocortices and hippocampi of the adult S1P2-deficient and S1P3-deficient mice
56
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