Small molecules which reverse CTNNB1 mutation
Canned Analysis
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General Information
AccessionDCA00022258
TitleSmall molecules which reverse CTNNB1 mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 mutation in the Embryonic Cardiac Progenitors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f22e467bea600fbaefa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2528
Cell TypeEmbryonic Cardiac Progenitors
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation Typemutation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM380347, GSM380348, GSM380349
Perturbed SamplesGSM380350, GSM380351, GSM380352
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15232
Gene Expression Omnibus
-Catenin stabilized cardiac progenitor cells in vivo
7
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