Small molecules which reverse NFKBIZ KO
Canned Analysis
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General Information
AccessionDCA00022260
TitleSmall molecules which reverse NFKBIZ KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NFKBIZ KO in the peritoneal macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f18e467bea600fbaef6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2529
Cell Typeperitoneal macrophages
Gene Symbol (human)NFKBIZ
Gene Symbol (mouse)Nfkbiz
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1055994, GSM1055995, GSM1055997
Perturbed SamplesGSM1056004, GSM1056006, GSM1056008
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43075
Gene Expression Omnibus
Lipopolysaccharide-stimulated, NFB inhibitor (IB) deficient-peritoneal macrophages
7
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