Small molecules which reverse GATA3 OE
Canned Analysis
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General Information
AccessionDCA00022264
TitleSmall molecules which reverse GATA3 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GATA3 OE in the R1 embryonic stem cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d224f7e467bea600fbb186
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2531
Cell TypeR1 embryonic stem cell line
Gene Symbol (human)GATA3
Gene Symbol (mouse)Gata3
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM325450, GSM325451, GSM325452, GSM325453, GSM325454, GSM325455, GSM325459
Perturbed SamplesGSM325456, GSM325457, GSM325458
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE12999
Gene Expression Omnibus
Cdx2 and Gata3 overexpression effect on R1 embryonic stem cell line
7
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