Small molecules which reverse PLAGL2 OE
Canned Analysis
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General Information
AccessionDCA00022296
TitleSmall molecules which reverse PLAGL2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PLAGL2 OE in the primary p53-null neural stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d229a1e467bea600fbb39a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorstevann
CREEDS IDgene:2546
Cell Typeprimary p53-null neural stem cells
Gene Symbol (human)PLAGL2
Gene Symbol (mouse)Plagl2
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM529445, GSM529449, GSM529451
Perturbed SamplesGSM529448, GSM529450, GSM529452
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21143
Gene Expression Omnibus
Zinc finger transcription factor PLAGL2 effect on primary p53-null neural stem cells
7
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