Small molecules which mimic IKZF1 KO
Canned Analysis
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General Information
AccessionDCA00022297
TitleSmall molecules which mimic IKZF1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IKZF1 KO in the DN4 thymocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22996e467bea600fbb394
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2547
Cell TypeDN4 thymocytes
Gene Symbol (human)IKZF1
Gene Symbol (mouse)Ikzf1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1123187, GSM1123189
Perturbed SamplesGSM1123186, GSM1123188
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE46093
Gene Expression Omnibus
Gene expression in DN4 thymocytes from mice with an inducible deletion of Ikaros
7
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