Small molecules which reverse CREM KO
Canned Analysis
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General Information
AccessionDCA00022302
TitleSmall molecules which reverse CREM KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CREM KO in the adrenal gland cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22ed8e467bea600fbb5e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2558
Cell Typeadrenal gland
Gene Symbol (human)CREM
Gene Symbol (mouse)Crem
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM732628, GSM732633, GSM732634, GSM732635, GSM732636
Perturbed SamplesGSM732627, GSM732629, GSM732630, GSM732631, GSM732632
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29592
Gene Expression Omnibus
The effect of Crem absence on gene expression in mouse adrenal glands.
7
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