Small molecules which mimic NOTCH1 Reactivation (WASHOUT - 4 Hours)
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022321
TitleSmall molecules which mimic NOTCH1 Reactivation (WASHOUT - 4 Hours)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NOTCH1 Reactivation (WASHOUT - 4 Hours) in the CUTLL1 MigR1 transduced (T-lymphoblastic leukemia) cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23981e467bea600fbba98
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2570
Cell TypeCUTLL1 MigR1 transduced (T-lymphoblastic leukemia) cell line
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismhuman
Perturbation TypeReactivation (WASHOUT - 4 Hours)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM731527, GSM731528, GSM731529
Perturbed SamplesGSM731534, GSM731535, GSM731536
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29544
Gene Expression Omnibus
Notch-on and Notch-off effects on T-lymphoblastic leukemia cell line CUTLL1: time course
35
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.