Small molecules which reverse STUB1 KO
Canned Analysis
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General Information
AccessionDCA00022348
TitleSmall molecules which reverse STUB1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by STUB1 KO in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1efe7e467bea600fb9ab0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2581
Cell Typeheart
Gene Symbol (human)STUB1
Gene Symbol (mouse)Stub1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1442228, GSM1442229, GSM1442230
Perturbed SamplesGSM1442231, GSM1442232, GSM1442233
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59672
Gene Expression Omnibus
Expression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
7
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