Small molecules which reverse CTNNB1 KO
Canned Analysis
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General Information
AccessionDCA00022352
TitleSmall molecules which reverse CTNNB1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 KO in the BxPC3 pancreatic adenocarcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eff8e467bea600fb9ab8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2583
Cell TypeBxPC3 pancreatic adenocarcinoma cells
Gene Symbol (human)CTNNB1
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1539909, GSM1539910, GSM1539911, GSM1539912, GSM1539913, GSM1539915
Perturbed SamplesGSM1539916, GSM1539917, GSM1539918, GSM1539919, GSM1539920, GSM1539921, GSM1539922, GSM1539923, GSM1539924, GSM1539925, GSM1539926, GSM1539927
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63072
Gene Expression Omnibus
Global gene expression analysis comparing wild type and beta catenin deficient BxPC3 pancreatic adenocarcinoma cells.
7
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