Small molecules which mimic CALCR KO
Canned Analysis
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General Information
AccessionDCA00022353
TitleSmall molecules which mimic CALCR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CALCR KO in the Osteoclasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f010e467bea600fb9ac2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2584
Cell TypeOsteoclasts
Gene Symbol (human)CALCR
Gene Symbol (mouse)Calcr
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1487524, GSM1487525, GSM1487526
Perturbed SamplesGSM1487530, GSM1487531, GSM1487532
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE60761
Gene Expression Omnibus
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
21
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