Small molecules which reverse BCL2 OE
Canned Analysis
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General Information
AccessionDCA00022356
TitleSmall molecules which reverse BCL2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BCL2 OE in the Tissue: Spleen Type: Saline Strain: C57BL/6 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f025e467bea600fb9acc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2586
Cell TypeTissue: Spleen Type: Saline Strain: C57BL/6
Gene Symbol (human)BCL2
Gene Symbol (mouse)Bcl2
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM135711, GSM135712, GSM135713, GSM135721, GSM135722
Perturbed SamplesGSM135705, GSM135706, GSM135707, GSM135717, GSM135718
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5811
Gene Expression Omnibus
Surviving Sepsis: bcl-2 Overexpression Modulates Splenocyte Transcriptional Responses in vivo
28
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