Small molecules which reverse YAP1 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022364
TitleSmall molecules which reverse YAP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by YAP1 KD in the HUVEC (Human umbilical vein endothelial cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f037e467bea600fb9ad4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2588
Cell TypeHUVEC (Human umbilical vein endothelial cells)
Gene Symbol (human)YAP1
Gene Symbol (mouse)Yap1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1517967, GSM1517968, GSM1517969, GSM1517970
Perturbed SamplesGSM1517971, GSM1517972, GSM1517973, GSM1517974, GSM1517975, GSM1517976, GSM1517977, GSM1517978
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE61989
Gene Expression Omnibus
YAP transcriptional regulator depletion effect on endothelial cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.