Small molecules which reverse PSMC4 KO
Canned Analysis
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General Information
AccessionDCA00022370
TitleSmall molecules which reverse PSMC4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PSMC4 KO in the skeletal muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f590e467bea600fb9d24
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2594
Cell Typeskeletal muscle
Gene Symbol (human)PSMC4
Gene Symbol (mouse)Psmc4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM857256, GSM857257, GSM857258
Perturbed SamplesGSM857253, GSM857254, GSM857255
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34896
Gene Expression Omnibus
Muscle specific proteasome deficient mice
7
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