Small molecules which reverse FLNB KO
Canned Analysis
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General Information
AccessionDCA00022372
TitleSmall molecules which reverse FLNB KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FLNB KO in the murine kidney, cystic epithelial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f57de467bea600fb9d1c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2596
Cell Typemurine kidney, cystic epithelial tissue
Gene Symbol (human)FLNB
Gene Symbol (mouse)Flnb
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM266130, GSM266131, GSM266132
Perturbed SamplesGSM266133, GSM266134, GSM266135
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10989
Gene Expression Omnibus
Expression data of cystic renal epithelial tissue from mice deficient for fumarate hydratase.
7
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