Small molecules which mimic KDM1B KD
Canned Analysis
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General Information
AccessionDCA00022389
TitleSmall molecules which mimic KDM1B KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KDM1B KD in the HeLa cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d232c2e467bea600fbb79c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:2611
Cell TypeHeLa cells
Gene Symbol (human)KDM1B
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM564835, GSM564836
Perturbed SamplesGSM564833, GSM564834
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE22859
Gene Expression Omnibus
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating H3K4me2 methylation (Affymetrix)
7
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