Small molecules which mimic SOX2 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022399
TitleSmall molecules which mimic SOX2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SOX2 KD in the mOS-482 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23356e467bea600fbb7de
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:2616
Cell TypemOS-482 cells
Gene Symbol (human)SOX2
Gene Symbol (mouse)Sox2
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1585264, GSM1585265, GSM1585266
Perturbed SamplesGSM1585267, GSM1585268, GSM1585269
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE64965
Gene Expression Omnibus
Expression profile of osteosarcoma cells in which Sox2 maintains cancer stem cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.