Small molecules which reverse NRL Deficiency
Canned Analysis
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General Information
AccessionDCA00022408
TitleSmall molecules which reverse NRL Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NRL Deficiency in the Photoreceptors cells of retinas at P6 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f485e467bea600fb9cb0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:264
Cell TypePhotoreceptors cells of retinas at P6
Gene Symbol (human)NRL
Gene Symbol (mouse)Nrl
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM92645, GSM92646, GSM92647, GSM92648
Perturbed SamplesGSM92625, GSM92626, GSM92627, GSM92628
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4051
Gene Expression Omnibus
Transcription factor Nrl deficiency effect on photoreceptor development
42
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