Small molecules which reverse ELANE Inhibition
Canned Analysis
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General Information
AccessionDCA00022416
TitleSmall molecules which reverse ELANE Inhibition
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ELANE Inhibition in the Mepenzolate bromide effect on lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20a4ae467bea600fba602
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2622
Cell TypeMepenzolate bromide effect on lung
Gene Symbol (human)ELANE
Gene Symbol (mouse)Elane
Organismmouse
Perturbation TypeInhibition
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1230990, GSM1230991, GSM1230992, GSM1230993
Perturbed SamplesGSM1230986, GSM1230987, GSM1230988, GSM1230989
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50836
Gene Expression Omnibus
Mepenzolate bromide effect on lung: time course
21
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