Small molecules which reverse PBX1 Expression
Canned Analysis
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General Information
AccessionDCA00022420
TitleSmall molecules which reverse PBX1 Expression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PBX1 Expression in the CD4+ T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20a78e467bea600fba616
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2627
Cell TypeCD4+ T cells
Gene Symbol (human)PBX1
Gene Symbol (mouse)Pbx1
Organismmouse
Perturbation TypeExpression
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM555381, GSM555382, GSM555383, GSM555384
Perturbed SamplesGSM555385, GSM555386, GSM555387, GSM555388
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE22313
Gene Expression Omnibus
Lupus susceptibility locus Sle1a.1 in murine model of lupus: CD4+ T cells
7
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