Small molecules which reverse GATA4 KO
Canned Analysis
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General Information
AccessionDCA00022430
TitleSmall molecules which reverse GATA4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GATA4 KO in the Myoblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20fece467bea600fba882
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:2656
Cell TypeMyoblast
Gene Symbol (human)GATA4
Gene Symbol (mouse)Gata4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1612842, GSM1612843, GSM1612844
Perturbed SamplesGSM1612845, GSM1612846, GSM1612847
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE66016
Gene Expression Omnibus
Skeletal muscle myoblasts: GATA4-Wt, -KO, -OE; day 0, 3
21
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