Small molecules which reverse EZH2 KO
Canned Analysis
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General Information
AccessionDCA00022450
TitleSmall molecules which reverse EZH2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EZH2 KO in the LNCaP cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22e71e467bea600fbb5ba
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2664
Cell TypeLNCaP
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM969458, GSM969460, GSM969462
Perturbed SamplesGSM969459, GSM969461, GSM969463
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39452
Gene Expression Omnibus
Expression data of EZH2-dependent genes in prostate cancer cell lines
12
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