Small molecules which reverse KLF3 KO
Canned Analysis
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General Information
AccessionDCA00022462
TitleSmall molecules which reverse KLF3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KLF3 KO in the TER119+ erythroblast cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21bafe467bea600fbada6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2672
Cell TypeTER119+ erythroblast cells
Gene Symbol (human)KLF3
Gene Symbol (mouse)Klf3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM871355, GSM871356, GSM871357, GSM871358
Perturbed SamplesGSM871352, GSM871353, GSM871354
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE35592
Gene Expression Omnibus
Microarray analysis of wildtype and Klf3 KO E14.5 fetal liver cells (TER119- and TER119+)
14
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