Small molecules which mimic PDE6B rd1 mutation
Canned Analysis
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General Information
AccessionDCA00022473
TitleSmall molecules which mimic PDE6B rd1 mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PDE6B rd1 mutation in the Retina cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ddde467bea600fba798
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2985
Cell TypeRetina
Gene Symbol (human)PDE6B
Gene Symbol (mouse)Pde6b
Organismmouse
Perturbation Typerd1 mutation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1024803, GSM1024804, GSM1024805, GSM1024806, GSM1024807, GSM1024808, GSM1024809, GSM1024810, GSM1024811, GSM1024812, GSM1024813, GSM1024814, GSM1024815, GSM1024816, GSM1024817, GSM1024818
Perturbed SamplesGSM1024819, GSM1024820, GSM1024821, GSM1024822, GSM1024823, GSM1024824, GSM1024825, GSM1024826, GSM1024827, GSM1024828, GSM1024829, GSM1024830, GSM1024831, GSM1024832, GSM1024833, GSM1024834
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41821
Gene Expression Omnibus
rd1 model of retinal degeneration: time course
35
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