Small molecules which mimic CASP1 KO
Canned Analysis
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General Information
AccessionDCA00022477
TitleSmall molecules which mimic CASP1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CASP1 KO in the epididymal white adipose tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c57e467bea600fbadc4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2679
Cell Typeepididymal white adipose tissue
Gene Symbol (human)CASP1
Gene Symbol (mouse)Casp1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM619229, GSM619230, GSM619231, GSM619232
Perturbed SamplesGSM619226, GSM619227, GSM619228
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE25205
Gene Expression Omnibus
Inflammasome-compromised epidydimal white adipose response to a high fat diet
14
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