Small molecules which mimic ARX KO
Canned Analysis
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General Information
AccessionDCA00022503
TitleSmall molecules which mimic ARX KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ARX KO in the brain (subpallium, Pou3f-expressing cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d227f9e467bea600fbb2dc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcarlfulp
CREEDS IDgene:27
Cell Typebrain (subpallium, Pou3f-expressing cells)
Gene Symbol (human)ARX
Gene Symbol (mouse)Arx
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM315884, GSM315886, GSM315888, GSM315891
Perturbed SamplesGSM315885, GSM315887, GSM315889, GSM315890
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE12609
Gene Expression Omnibus
Transcription factor Arx null brains (fulp-affy-mouse-364520)
7
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