Small molecules which mimic BACH2 KO
Canned Analysis
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General Information
AccessionDCA00022505
TitleSmall molecules which mimic BACH2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by BACH2 KO in the Pre-B ALL cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22d12e467bea600fbb520
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2701
Cell TypePre-B ALL cells
Gene Symbol (human)BACH2
Gene Symbol (mouse)Bach2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM766000, GSM766017, GSM766018
Perturbed SamplesGSM766022, GSM766023, GSM766057
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30883
Gene Expression Omnibus
Role and function of Bach2 in BCR-ABL1 driven pre-B ALL
14
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