Small molecules which reverse HRAS OE
Canned Analysis
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General Information
AccessionDCA00022510
TitleSmall molecules which reverse HRAS OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HRAS OE in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20686e467bea600fba45a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorwokeefe
CREEDS IDgene:2708
Cell Typeheart
Gene Symbol (human)HRAS
Gene Symbol (mouse)Hras
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM80525, GSM80526
Perturbed SamplesGSM80551, GSM80552, GSM80553
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3530
Gene Expression Omnibus
MAP kinase activation effect on heart: time course
70
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