Small molecules which reverse HRAS Selective cardiac induced overexpression of the gene for in male
Canned Analysis
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General Information
AccessionDCA00022514
TitleSmall molecules which reverse HRAS Selective cardiac induced overexpression of the gene for in male
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HRAS Selective cardiac induced overexpression of the gene for in male in the cardiac tissue harvested 4-7 days post overexpression induction cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc19e467bea600fb9fc4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:984
Cell Typecardiac tissue harvested 4-7 days post overexpression induction
Gene Symbol (human)HRAS
Gene Symbol (mouse)Hras
Organismmouse
Perturbation TypeSelective cardiac induced overexpression of the gene for in male
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM80525, GSM80526, GSM80527
Perturbed SamplesGSM80545, GSM80546, GSM80547
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3530
Gene Expression Omnibus
MAP kinase activation effect on heart: time course
70
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