Small molecules which mimic HRAS perturbation
Canned Analysis
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General Information
AccessionDCA00022515
TitleSmall molecules which mimic HRAS perturbation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HRAS perturbation in the cardiac tissue harvested 2-4 weeks post overexpression induction cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc1fe467bea600fb9fc6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:985
Cell Typecardiac tissue harvested 2-4 weeks post overexpression induction
Gene Symbol (human)HRAS
Gene Symbol (mouse)Hras
Organismmouse
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM80525, GSM80526, GSM80527
Perturbed SamplesGSM80551, GSM80552, GSM80553
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3530
Gene Expression Omnibus
MAP kinase activation effect on heart: time course
70
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