Small molecules which reverse ARNTL KO
Canned Analysis
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General Information
AccessionDCA00022530
TitleSmall molecules which reverse ARNTL KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ARNTL KO in the dorsal skin basal interfollicular epidermal stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22816e467bea600fbb2ea
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2710
Cell Typedorsal skin basal interfollicular epidermal stem cells
Gene Symbol (human)ARNTL
Gene Symbol (mouse)Arntl
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM668416, GSM668417, GSM668418
Perturbed SamplesGSM668419, GSM668420, GSM668421
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE27079
Gene Expression Omnibus
Expression data from epidermal stem cells isolated from dorsal skin of P19 Per1-Venus mice and Bmal1 epidermal knockout mice
7
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