Small molecules which mimic LMNA OE
Canned Analysis
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General Information
AccessionDCA00022533
TitleSmall molecules which mimic LMNA OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LMNA OE in the fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fcb5e467bea600fba006
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormjafari
CREEDS IDgene:2715
Cell Typefibroblasts
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM992926, GSM992927
Perturbed SamplesGSM992923, GSM992924, GSM992925, GSM992928, GSM992929
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40404
Gene Expression Omnibus
Progeroid and revertant phenotypes in primary dermal fibroblast cell line GM00038
7
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