Small molecules which reverse WT1 OE
Canned Analysis
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General Information
AccessionDCA00022542
TitleSmall molecules which reverse WT1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by WT1 OE in the U2OS osteosarcoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fba2e467bea600fb9f90
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:2720
Cell TypeU2OS osteosarcoma cells
Gene Symbol (human)WT1
Gene Symbol (mouse)Wt1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM115523, GSM115525
Perturbed SamplesGSM115522, GSM115524
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5117
Gene Expression Omnibus
Wilms' tumor suppressor (WT1) targets: time course
7
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