Small molecules which mimic LEP KO
Canned Analysis
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General Information
AccessionDCA00022543
TitleSmall molecules which mimic LEP KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LEP KO in the gallbladder cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fba9e467bea600fb9f92
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormjafari
CREEDS IDgene:2723
Cell Typegallbladder
Gene Symbol (human)LEP
Gene Symbol (mouse)Lep
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM74190, GSM74191, GSM74192, GSM74194
Perturbed SamplesGSM74081, GSM74083, GSM74171, GSM74189
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3293
Gene Expression Omnibus
Leptin effect on gallbladder
12
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