Small molecules which mimic ATM KO
Canned Analysis
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General Information
AccessionDCA00022545
TitleSmall molecules which mimic ATM KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ATM KO in the lymphoid tumors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fb84e467bea600fb9f82
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormjafari
CREEDS IDgene:2724
Cell Typelymphoid tumors
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismmouse
Perturbation TypeKO
None{u'vals': [0.0878305770244, 0.0763540243546, 0.0650535918068, -0.0641670871877, -0.0641075080394, -0.0602462282613, -0.0580036641796, 0.05597441706, 0.0558566976217, 0.0527556181896, 0.0513404928536, -0.0505345033201, -0.0504164651026, -0.0494108127559, 0
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM38269, GSM38270, GSM38271, GSM38272, GSM38273, GSM38274, GSM38275
Perturbed SamplesGSM38262, GSM38263, GSM38264, GSM38265, GSM38266, GSM38267, GSM38268
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2118
Gene Expression Omnibus
Ionizing radiation effect on lymphoid tissue of ATM protein kinase deficient mutants
14
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