Small molecules which mimic ATM Deficiency
Canned Analysis
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General Information
AccessionDCA00022547
TitleSmall molecules which mimic ATM Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ATM Deficiency in the Lymph nodes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d214e0e467bea600fbaaa8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:796
Cell TypeLymph nodes
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismmouse
Perturbation TypeDeficiency
None{u'vals': [0.0599947577797, 0.0579906697969, 0.0564030085216, 0.0563898248511, 0.0547178740364, 0.0543159169469, 0.0541554169289, 0.0540089586907, 0.0539091465608, -0.0528069549591, -0.0512684823839, 0.0501014456585, 0.0499440381979, 0.0488469499342, 0.04
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM38262, GSM38263, GSM38264
Perturbed SamplesGSM38269, GSM38270, GSM38271
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2118
Gene Expression Omnibus
Ionizing radiation effect on lymphoid tissue of ATM protein kinase deficient mutants
14
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