Small molecules which reverse PTEN KD
Canned Analysis
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General Information
AccessionDCA00022580
TitleSmall molecules which reverse PTEN KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PTEN KD in the MEF cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d219ece467bea600fbace2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormauroccm
CREEDS IDgene:2875
Cell TypeMEF
Gene Symbol (human)PTEN
Gene Symbol (mouse)Pten
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM718745, GSM718746
Perturbed SamplesGSM718749, GSM718750
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29010
Gene Expression Omnibus
Tumor suppressor PTEN re-expression effect on PTEN-null embryonic fibroblasts: time course
14
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