Small molecules which reverse ADRA2B KO
Canned Analysis
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General Information
AccessionDCA00022582
TitleSmall molecules which reverse ADRA2B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ADRA2B KO in the placenta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f083e467bea600fb9af4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2746
Cell Typeplacenta
Gene Symbol (human)ADRA2B
Gene Symbol (mouse)Adra2b
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM159348, GSM159349, GSM159350
Perturbed SamplesGSM159345, GSM159346, GSM159347
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6909
Gene Expression Omnibus
Alpha 2B-adrenoceptor deficient embryo and its placenta
7
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