Small molecules which mimic MMP7 KO
Canned Analysis
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General Information
AccessionDCA00022583
TitleSmall molecules which mimic MMP7 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MMP7 KO in the epithelium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f076e467bea600fb9aee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2747
Cell Typeepithelium
Gene Symbol (human)MMP7
Gene Symbol (mouse)Mmp7
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM196062, GSM196063, GSM196064
Perturbed SamplesGSM196070, GSM196071, GSM196072
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7957
Gene Expression Omnibus
Matrix metalloproteinase mutant airway epithelial cells response to Pseudomonas aeruginosa infection: time course
14
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