Small molecules which mimic DNMT1 Inhibition - (laccaic acid A)
Canned Analysis
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General Information
AccessionDCA00022599
TitleSmall molecules which mimic DNMT1 Inhibition - (laccaic acid A)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DNMT1 Inhibition - (laccaic acid A) in the MCF-7 BREAST CANCER cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23440e467bea600fbb846
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2762
Cell TypeMCF-7 BREAST CANCER cell line
Gene Symbol (human)DNMT1
Gene Symbol (mouse)Dnmt1
Organismhuman
Perturbation TypeInhibition - (laccaic acid A)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1115765, GSM1115767, GSM1115769
Perturbed SamplesGSM1115766, GSM1115768, GSM1115770
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45804
Gene Expression Omnibus
Laccaic acid effect on breast cancer cell line
12
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