Small molecules which reverse XBP1 KO
Canned Analysis
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General Information
AccessionDCA00022604
TitleSmall molecules which reverse XBP1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by XBP1 KO in the spleen CD11b Dendritic cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23466e467bea600fbb858
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKathaLahl
CREEDS IDgene:2766
Cell Typespleen CD11b Dendritic cells
Gene Symbol (human)XBP1
Gene Symbol (mouse)Xbp1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1277096, GSM1277097, GSM1277098
Perturbed SamplesGSM1277099, GSM1277100, GSM1277101
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52857
Gene Expression Omnibus
Expression data in splenic DC subsets in wild type and Xbp1 deficient mice
14
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