Small molecules which mimic RUNX1 KO
Canned Analysis
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General Information
AccessionDCA00022609
TitleSmall molecules which mimic RUNX1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RUNX1 KO in the Embryos at E8.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23da6e467bea600fbbc6a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:277
Cell TypeEmbryos at E8.5
Gene Symbol (human)RUNX1
Gene Symbol (mouse)Runx1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM48917, GSM48918
Perturbed SamplesGSM48919, GSM48920
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2592
Gene Expression Omnibus
Transcription factor RUNX1 knockout
21
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