Small molecules which mimic HES1 OE
Canned Analysis
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General Information
AccessionDCA00022617
TitleSmall molecules which mimic HES1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HES1 OE in the neurons cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d239fce467bea600fbbacc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKathaLahl
CREEDS IDgene:2771
Cell Typeneurons
Gene Symbol (human)HES1
Gene Symbol (mouse)Hes1
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1320013, GSM1320014, GSM1320015
Perturbed SamplesGSM1320010, GSM1320011, GSM1320012
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54622
Gene Expression Omnibus
Comparative gene expression profile of Hes1-overexpressing cultured hippocampal neurons vs the corresponding control populations (neurons expressing G...
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