Small molecules which reverse BCL6 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022620
TitleSmall molecules which reverse BCL6 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BCL6 KO in the T follicular helper cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d239ece467bea600fbbac6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKathaLahl
CREEDS IDgene:2772
Cell TypeT follicular helper cells
Gene Symbol (human)BCL6
Gene Symbol (mouse)Bcl6
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM995225, GSM995227
Perturbed SamplesGSM995221, GSM995223
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE40493
Gene Expression Omnibus
Bcl6 deficiency effect on regulatory T cell
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.