Small molecules which mimic IRF4 KO
Canned Analysis
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General Information
AccessionDCA00022621
TitleSmall molecules which mimic IRF4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IRF4 KO in the spleen B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a18e467bea600fbbad8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKathaLahl
CREEDS IDgene:2774
Cell Typespleen B cells
Gene Symbol (human)IRF4
Gene Symbol (mouse)Irf4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1255455, GSM1255456, GSM1255457, GSM1255458
Perturbed SamplesGSM1255459, GSM1255460, GSM1255461, GSM1255462
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51932
Gene Expression Omnibus
Expression data from murine irf4-/- and irf4+/+ mature B cells purified by magnetic cell separation
7
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