Small molecules which mimic KRT1 KO
Canned Analysis
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General Information
AccessionDCA00022623
TitleSmall molecules which mimic KRT1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KRT1 KO in the skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a05e467bea600fbbad0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorasingh
CREEDS IDgene:2776
Cell Typeskin
Gene Symbol (human)KRT1
Gene Symbol (mouse)Krt1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM815921, GSM815922, GSM815925
Perturbed SamplesGSM815915, GSM815916, GSM815918
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE32951
Gene Expression Omnibus
Genome-wide analysis of gene expression in Krt1+/+ versus Krt1-/- epidermis and full-thickness skin.
7
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