Small molecules which mimic VLDLR KO
Canned Analysis
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General Information
AccessionDCA00022625
TitleSmall molecules which mimic VLDLR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by VLDLR KO in the lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a0fe467bea600fbbad4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorasingh
CREEDS IDgene:2777
Cell Typelung
Gene Symbol (human)VLDLR
Gene Symbol (mouse)Vldlr
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1332383, GSM1332384, GSM1332385, GSM1332386
Perturbed SamplesGSM1332387, GSM1332388, GSM1332389, GSM1332390
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55247
Gene Expression Omnibus
Very low density lipoprotein receptor knockout effect in house dust mite model of asthma: lung
7
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